Description
三体第三部中 云天明的大脑被取出冰冻存 被三体人在太空捕获 并最终“复活”了云天明
这是依靠了三体文明有如魔法一样的高科技 还是基于现实生物学也具有可行性?
视频部分素材来自: Stanford Medicine, Harvard Medical School, Ted-ED, Howard Hughes Medical Institute, Science Magazine, Nature, 等Youtube上的公众科普频道;
学术论文的Supplemental video;
《新世纪福音战士》和《福音战士新剧场版》系列;
视频使用的BGM素材:
Evangelion 1.0 OST: EM20_Rhythem_Full
Neon Genesis Evangelion OST- Kanon D-Dur, Thanatos
Persona 5 OST- Life Will Change Instrumental
飞跃巅峰2 OST- 立つ鳥跡を濁さず
本视频中直接引用的文献:
(也发在评论区中)
胶质细胞和神经元的比例估算
Herculano-Houzel, S. (2014). The glia/neuron ratio: how it varies uniformly across brain structures and species and what that means for brain physiology and evolution. Glia 62, 1377-1391
胶质细胞iPSC重编程
Gao, X., Wang, X., Xiong, W., and Chen, J. (2016). In vivo reprogramming reactive glia into iPSCs to produce new neurons in the cortex following traumatic brain injury. Sci Rep 6, 22490.
原始态多能干细胞
Gafni, O., Weinberger, L., Mansour, A.A., Manor, Y.S., Chomsky, E., Ben-Yosef, D., Kalma, Y., Viukov, S., Maza, I., Zviran, A., et al. (2013). Derivation of novel human ground state naive pluripotent stem cells. Nature 504, 282-286.
全能干细胞
Mazid, M.A., Ward, C., Luo, Z., Liu, C., Li, Y., Lai, Y., Wu, L., Li, J., Jia, W., Jiang, Y., et al. (2022). Rolling back human pluripotent stem cells to an eight-cell embryo-like stage. Nature 605, 315-324.
Xu, Y., Zhao, J., Ren, Y., Wang, X., Lyu, Y., Xie, B., Sun, Y., Yuan, X., Liu, H., Yang, W., et al. (2022). Derivation of totipotent-like stem cells with blastocyst-like structure forming potential. Cell Res 32, 513-529.
合成老鼠胚胎
Tarazi, S., Aguilera-Castrejon, A., Joubran, C., Ghanem, N., Ashouokhi, S., Roncato, F., Wildschutz, E., Haddad, M., Oldak, B., Gomez-Cesar, E., et al. (2022). Post-gastrulation synthetic embryos generated ex utero from mouse naive ESCs. Cell 185, 3290-3306 e3225.
人脑的电镜扫描和3D重建(尚未正式发表)
Google Research Blog: A Browsable Petascale Reconstruction of the Human Cortex
https://ai.googleblog.com/2021/06/a-browsable-petascale-reconstruction-of.html